iPS Cells and Takeda Pharmaceutical's 10 Years: Professor Yamanaka Discusses Preparing to Cross the "Valley of Death"

京都大学iPS細胞研究所 Small Talk

This morning's coffee,Georgia European (Fragrant Black)It smells wonderful. This cup before work is essential for me; it helps me organize my thoughts.

I happened to see the news and it caught my attention, but Professor Shinya Yamanaka of Kyoto University andTakeda Pharmaceutical CompanyThis has been underway for 10 yearsJoint research program "T-CiRA"However, it seems that the contract will expire in fiscal year 2025. This project, which involved a massive investment of 20 billion yen, apparently hasn't yet resulted in a tangible product that's been released to the public. It would be a shame to simply dismiss this as "not yielding results."


This program was discovered by Professor YamanakaiPS cellsIt began with the aim of connecting this to the actual treatment of diseases and the development of new medicines. Since 2016, nearly 100 researchers have gathered to tackle intractable diseases such as cancer and heart failure. 。

Professor Yamanaka describes university research as the "hop" and the industry-academia collaboration of the past decade as the "step." It seems that there was an unavoidable preparation period before the "jump" to commercialization. 。

In the business world, we often face the "valley of death," where excellent ideas disappear without ever reaching the market. Professor Yamanaka also foresaw that iPS cells would one day face this challenge. 。

While it's true that none of these have reached commercialization in the last 10 years, they have certainly left a solid trail, including 58 patent applications and the emergence of startup companies that have progressed to the clinical trial stage. Takeda Pharmaceutical also stated that they have acquired a world-class research infrastructure by combining iPS cell technology with AI and automation. 。

Professor Yamanaka"Those who never give up will ultimately win."Those words strangely stuck with me. In an era where efficiency and speed are highly valued,I deliberately chose to "persevere patiently."But that might be the only key to jumping high. 。

The end of a major project is also the beginning of something new. Perhaps the work in front of us right now is still just a "step" in the process. Doesn't thinking about it that way make your perspective a little clearer?

Well, I've finished my coffee, so I think it's time to head to my desk. I believe that today's work will lead to a big leap forward in the future.

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